Use in specific populations. There is little information on specific dosage recommendations, although some literature states 2-3 g/day is a therapeutic dose. Patients with conditions such as diabetes, potassium levels, blood . . Stomach ulcers are painful sores in the lining of the stomach. For one, it may act by blocking enzymes that digest complex carbs, such as alpha-amylase. When using it, monitor your blood sugar regularly if you have diabetes. which enables users to obtain detailed information and reports based on their genome. and for pregnant or breastfeeding women. Learn more about causes and symptoms here. View abstract. Consult your doctor before supplementing with chanca piedra if you are on medication. According to some claims, chanca piedra may have several beneficial effects on different body systems. Xin-Hua, W., Chang-Qing, L., Xing-Bo, G., and Lin-Chun, F. A comparative study of Phyllanthus amarus compound and interferon in the treatment of chronic viral hepatitis B. Southeast Asian J Trop.Med Public Health 2001;32(1):140-142. Here is advice quoted from Frank Nice, Herbals and Breastfeeding: The nursing mother should take oral medications immediately following nursing, or right before the infant's longest sleep to avoid nursling exposure to a drug at its peak plasma level. In clinical studies with over 200 people with kidney stones, chanca piedra (Phyllanthus niruri) reduced their kidney stones, helping to clear the minerals and salt deposits [21, 22, 23, 24, 25, 26]. Pramyothin, P., Ngamtin, C., Poungshompoo, S., and Chaichantipyuth, C. Hepatoprotective activity of Phyllanthus amarus Schum. Theres no research on the long-term effects of chanca piedra, so it may be wise to limit the time you take the supplement to 12 weeks or less a duration that has been studied in humans (3). Phyllanthus niruri, or Chanca Piedra, is a small annual herb that grows and spreads much like a weed; it is native to the rainforests of the Amazon and other tropical areas, including the Bahamas, southern India, and China.Two other species, Phyllanthus amarus and Phyllanthus sellowianus, are closely related to P. niruri in appearance, phytochemical structure, and history of use, but are . Chanca piedra may help balance out these levels and prevent gout attacks. Stay on the safeside and avoid use. Its used in some traditional medicine practices as a gallstone treatment (1). This item Chanca Piedra 1600 mg - 120 Tablets Kidney Stone Crusher Gallbladder Support Peruvian Chanca Piedra Made in The USA Stone Breaker Chanca Piedra - Natural Kidney Cleanse & Gallbladder Formula - Detoxify Urinary Tract, Flush Impurities, Clear System - Hydrangea & Celery Seed Extract - 60 Vegetarian Soft Capsules Chanca Piedra is available as a supplement in capsule or tincture form. Okoli CO, Ibiam AF Ezike AC et al. Yeh, S. F., Hong, C. Y., Huang, Y. L., Liu, T. Y., Choo, K. B., and Chou, C. K. Effect of an extract from Phyllanthus amarus on hepatitis B surface antigen gene expression in human hepatoma cells. Rama Herbal Chanca Piedra Extract Tablets-60 Tablets Pack. Chanca Piedra increases the solubility of alkaline salts and help to maintain normal bacterial levels in the urogenital tract. Acetylcholine is a neurotransmitter mainly used by the rest-and-digest nervous system. View abstract. glimepiride, insulin, rosiglitazone, tolbutamide) might cause excessive drops in blood sugar levels [57, 73, 74]. International Journal of Pharmacognosy 1997;35(3):167-173. In about two-thirds of the participants, their kidney stones decreased in size and number. View abstract. Milne A, Hopkirk N, Lucas CR, et al. Consult your doctor before supplementing with chanca piedra. Karuna, R., Reddy, S. S., Baskar, R., and Saralakumari, D. Antioxidant potential of aqueous extract of Phyllanthus amarus in rats. Chanca piedra is available in various forms, including liquid drops, capsules, tablets, tea, and powder [1, 6, 23, 24]. In the rest of Asia, they are considered a remedy for digestive disorders, while in South America folks use them for urinary tract infections. West African Journal of Pharmacology and Drug Research 2007;42-50. and Thonn.). Chanca piedra is a medicinal herb used for over 2,000 years for a variety of diseases, including jaundice, kidney stones, gut disorders, and malaria. In a clinical study of 33 people with nerve damage caused by diabetes (also known as diabetic neuropathy), chanca piedra decreased pain and the sensation of numbness, tingling, and in the legs [92]. J Radiat.Res 2009;50(4):303-309. Zhu FM, Zhang JQ Zhang XZ et al. Colombia Medica 2007;132-139. Clark BC, Georgekutty J, Berul CI. Raphael, K. R., Sabu, M., Kumar, K. H., and Kuttan, R. Inhibition of N-Methyl N'-nitro-N-nitrosoguanidine (MNNG) induced gastric carcinogenesis by Phyllanthus amarus extract. Pharm Biol 2019;57(1):145-53. TRADITIONAL HERB: Chanca Piedra has been a staple to Native American herbal practices for centuries ; PREMIUM SUPPORT: Each serving provides 500 mg of Chanca Piedra, in optimal quick-release capsules ; . Wang LT, He Y Ren JW Jiang J et al. Traditionally, this plant was used for abortions and may cause abnormalities with the fetus. In small clinical studies with 30 people,chanca piedra (the Phyllanthus amarus species) lowered their blood sugar levels. This herb may act by [142, 148, 124, 143, 85, 84, 145, 146, 147]: In mice, chanca piedra improved memory and reversed amnesia [149]. Chanca piedra is available in teas, liquid extracts, capsules, or tablets. View abstract. Consult your doctor before supplementing with chanca piedra if you are on medication. Int J Clin Pharmacol.Ther 2008;46(6):295-306. Because chanca piedra is not approved by the FDA for any conditions, there is no official dose. Clinical observation on 40 cases of chronic hepatitis B using compound Phyllanthus amarus combined with interferon. Although theres a small amount of evidence to support the use of chanca piedra for kidney stones in humans, larger and more rigorous human studies are needed to determine if chanca piedra truly has any benefits. 1996;39(3):211-215. Raintree tropical plant database, Amazon plants. Plus, it contains some potential cancer-fighting compounds that have yet to be further explored [6, 1, 2, 7]. View abstract. 2015;5(6):512-9. It also decreased oxidative stress and prevented liver damage [38]. Your email address will not be published. While chanca piedra may reduce blood sugar and blood pressure levels, it should be used with caution if youre already on medication for lowering blood pressure or blood sugar. Indian J Biochem Biophys. Antiviral Res 2004;64(2):93-102. Niu, J. They wanted to understand the traditional use of this plant by indigenous people. Asian Pac.J Cancer Prev. 7. They are a type of peptic ulcer disease. Clinical study of hepatoprotective drug Phyllanthus amarus. Hepatitis B anti-inflammatory viral infection of the liver which can be life-threatening if not treated well. View abstract. However, this doesnt necessarily translate to an oral supplement being effective against stomach ulcers in humans (5, 6). Drug Interactions. 2005;12(6-7):494-500. it's best to avoid it while pregnant, trying to get pregnant, or breastfeeding . Vijayanand V, Nagarajan B Vasu K. Efficacy of Azadirachta indica and Phyllanthus amarus in experimental hepatitis in dogs. Foo LY. The effect of Phyllanthus niruri on urinary inhibitors of calcium oxalate crystallization and other factors associated with renal stone formation. Not all gallstones and kidney stones are created equal however. Taking chanca piedra along with diabetes medications might cause blood sugar to drop too low. 3.3 out of 5 stars (3.3) 5. Biol.Pharm.Bull. 5. Plant Cell, Tissue and Organ Culture 2011;101-110. Do not under any circumstances attempt to replace conventional cancer therapies with chanca piedra or any other supplements. A study of the effect of Phyllanthus amarus extracts on blood glucose in rabbits. The contents of the bottles and the benefits listed below are the same for both product labels. et Thonn. Both Phyllanthus niruri and P. amarus have been called chanca piedra. View abstract. Chanca Piedra has numerous health benefits as it is rich in different types of chemicals which helps in relieving fever and spasms. Breast-feeding: There isn't enough reliable information to know if chanca piedra is safe to use while breast-feeding. 1. Joshi H, Parle M. Evaluation of the antiamnesic effects of Phyllanthus amarus in mice. It supports a healthy cholesterol balance and may reduce hypertension, helping to support heart health. Urol.Res 2004;32(5):362-366. And if you think these uses sound too wide-ranging for just one plant species, youre right. View abstract. Animal and cell-based studies reveal chanca piedra contains powerful antioxidant, anti-inflammatory, anti-cancer, and antibacterial compounds. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. Gastroprotective effect of Phyllanthus niruri leaf extract against ethanol-induced gastric mucosal injury in rats. 2013;146(1):318-23. Learn more. View abstract. Where to Buy Chanca Piedra. View abstract. Current Science 2003;84(4):529-533. Since there is not enough reliable evidence to determine the effects while breast feeding, it is best to simply not take Chanca Piedra while breastfeeding. It is possible that taking chanca piedra will cause bleeding in people. Protocol for callus culture of Phyllanthus amarus Schum and Thonn. He strongly believes that scientific literacy is crucial to maintain a healthy lifestyle and avoid falling for scams. 16. Raphael, K. R., Sabu, M. C., and Kuttan, R. Hypoglycemic effect of methanol extract of Phyllanthus amarus Schum & Thonn on alloxan induced diabetes mellitus in rats and its relation with antioxidant potential. Supposedly, it contains phytochemicals or plant compounds that can increase urine flow, kill harmful bacteria and viruses, and relieve inflammation (1). Z., Wang, Y. Y., Qiao, M., Gowans, E., Edwards, P., Thyagarajan, S. P., Gust, I., and Locarnini, S. Effect of Phyllanthus amarus on duck hepatitis B virus replication in vivo. Furthermore, the few clinical trials that were carried out had a small number of participants and some of their findings are debatable. Paris: Lavoisier Publishing, 1995. 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