You may report side effects to FDA at 1-800-FDA-1088. Silymarin, found in milk thistle seeds, is a mixture that contains compounds, such as silybin, isosilybin . Han YU, Guo D, Chen Y, et al. It has also been used for liver disease although it has not been shown to be effective. No supplement is intended to treat, cure, or prevent disease. Sebagai suplemen makanan, minum 1-2 kapsul setiap hari sebaiknya dengan makanan atau seperti . What. Allergic reactions, abdominal problems, and estrogen and drug interactions are some of the common side effects seen in people who take this herb for extended durations. Milk thistle is native to Europe and was introduced into North America by early colonists. Voroneanu L, Nistor I, Dumea R, Apetrii M, Covic A. Silymarin in type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials. By Brittany Lubeck, RD You may report side effects to Health Canada at 1-866-234-2345. This article explores potential milk thistle benefits and examines whether there is any scientific evidence to support its use. Yes, you can take milk thistle long term. Spiny stems branch at the top and reach heights of 5 to 10 feet. He specializes Professional Certificate In Food, Nutrition & Health. ), SAGE Journals. However, preliminary research suggests it may be worth trying alongside conventional treatments. Effects and tolerance of silymarin (milk thistle) in chronic hepatitis C virus infection patients: a meta-analysis of randomized controlled trials. Some people also call it Mary thistle and holy thistle. US residents can call their local poison control center at 1-800-222-1222. Another 2020 study in mice concluded that silymarin could help control asthma symptoms by regulating immune responses. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial. Some of these drugs may include Mevacor, Lescol, Zocor, Pravachol, and Baycol. Keep in mind, though, that it is unknown if milk thistle tea provides the same suggested benefits as milk thistle supplements. A service of the National Library of Medicine, PubMed contains publication information and (in most cases) brief summaries of articles from scientific and medical journals. What Are the Side Effects of Milk Thistle? This is not a complete list of side effects and others may occur. How should we deal with preliminary information such as this? Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox. No related drugs found for this medication. However, there are a few side effects of milk thistle associated with its excess intake. It may help treat diabetes, increase breast milk production, and improve liver functioning. You might also get the herb at your nearest supermarket/pharmacy. Milk thistle may interact with certain medications. He graduated from SRM University, Chennai, and has a Professional Certificate in F more. Effect of silymarin on biochemical indicators in patients with liver disease: systematic review with meta-analysis. Consult your doctor before breast-feeding. The extract of the seeds of milk thistle contains a number of substances, collectively called silymarin. Researchers must carry out further studies on humans to identify what benefits a person can expect from applying milk thistle to their skin. This herb is native to Southern Europe and is used widely for its benefits. However, the review's authors warned that the quality of the studies was poor and that more research is needed before milk thistle should be recommended for use. Milk thistle may interfere with the following medications, because both milk thistle and these medications are broken down by the same liver enzymes: Reviewed By: Steven D. Ehrlich, N.M.D., private practice specializing in complementary and alternative medicine, Phoenix, AZ. Bethesda (MD): National Library of Medicine (US); February 20, 2022. Other studies looking at milk thistle for cirrhosis have found conflicting results. Bunchorntavakul C, Wootthananont T, Atsawarungruangkit A. Check with your physician if you have any of the. Therefore, it is not known whether milk thistle or silymarin should be used to treat cirrhosis. Deng JW, Shon JH, Shin HJ, et al. Call your doctor for medical advice about side effects. JAMA. Milk Thistle: Effects on Liver Disease and Cirrhosis and Clinical Adverse Effects: Summary, AHRQ Evidence Report Summeries, National Center for Biotechnology Information, U.S. National Library of Medicine. Articles on StyleCraze are backed by verified information from peer-reviewed and academic research papers, reputed organizations, research institutions, and medical associations to ensure accuracy and relevance. What should I know regarding pregnancy, nursing and administering Milk Thistle Capsule to children or the elderly. Wu J-W, Lin L-C, Tsai T-H. Drugdrug interactions of silymarin on the perspective of pharmacokinetics. But it may be a helpful complementary treatment to try if a healthcare professional approves it. The terms "milk thistle" and "silymarin" are often used interchangeably. Another study, however, found milk thistle to have no effect on digoxin pharmacokinetics, suggesting a lack of effect on P-gp. Silymarin as supportive treatment in liver diseases: a narrative review. Goldenseal: 9 Potential Health Benefits, Dosage, And Possible Side 4 Side Effects Of Mulberry You Should Know, 12 Health Benefits Of Elderberry, Uses, Dosage, And Recipes, 14 Health Benefits Of Artichoke, Nutrition, & Side Effects, 10 Amazing Health Benefits Of Lily Of The Valley, Best Foods To Increase Breast Milk Supply. However, there is a lack of . A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. It is not intended to substitute for the medical expertise and advice of your health care provider(s). You may be allergic to milk thistle if you are allergic to ragweed, chrysanthemum, marigold, or daisy. Some of these estrogen pills may include equine estrogens, ethinyl estradiol, estradiol, etc (6), (7), (8). Highly clinically significant. Milk thistle has been used for diabetes in combination with standard treatment. Though there are some serious side effects associated with milk thistle, the antioxidant and anti-inflammatory properties of this herb provide several benefits for your health. Silybum marianum is a species of thistle.It has various common names including milk thistle, blessed milkthistle, Marian thistle, Mary thistle, Saint Mary's thistle, Mediterranean milk thistle, variegated thistle and Scotch thistle (though not to be confused with Onopordum acanthium or Cirsium vulgare).This species is an annual or biennial plant of the family Asteraceae. If you buy through links on this page, we may earn a small commission Heres our process. Although research is still emerging, milk thistle may be beneficial for conditions relating to the liver and gallbladder. Effects of Silybum marianum (L.) Gaertn. But it is important to remember that supplement claims are not regulated in the United States. Milk thistle (Silybum marianum) contains silymarin which is a mixture of flavonolignans, mainly silibinin (also known as silybin), as well as silycristine, silydianin, quercetin and taxifolin. Call your doctor for medical advice about side effects. Dosage is also typically listed on the nutrition label of supplements. Take charge of your healthtalk with your health care providers about any complementary health approaches you use. Milk thistle is an herbal remedy with rich plant compounds. Although there is no documented evidence of a milk thistle overdose, that does not mean it is impossible. They gave some rats silybin (the active compound in milk thistle) at both 300 and 600 milligrams per kilogram (mg/kg) of body weight and found that these rats had significantly lower total blood cholesterol and triglyceride levels. Liver cleanses promise to rid the body of toxins and impurities, but are controversial because there is little science to support their use. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. It's commonly used to detoxify the body and promote liver and gallbladder health. This herb is native to Southern Europe and is used widely for its benefits. 2014;11(2):167-74. doi:10.1900/RDS.2014.11.167. Milk thistle side effects (more detail) A 2020 narrative review detailing silymarin's potential uses for the liver noted its antioxidant-like effects in people with cirrhosis. Silymarin in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. What is the daily upper limit for milk thistle? It is now found throughout the world. Hepatology. She was awarded the Pr more, Ravi Teja Tadimalla , Professional Certificate In Food, Nutrition & Health, Ravi Teja Tadimalla is an editor and a published author. 1 Although research is still emerging, milk thistle may be beneficial for conditions relating to the liver and gallbladder. An older study found that milk thistle extract had a positive effect on immune response in humans. Brittany Lubeck, RD, is a nutrition writer and registered dietitian with a master's degree in clinical nutrition. 2016;5147468. doi:10.1155/2016/5147468. If you have any questions about storage, ask your pharmacist. Milk thistle may help to stop the spread of certain types of cancer. Drug-drug Interactions of Silymarin on the Perspective of Pharmacokinetics, Journal of Ethnopharmacology, US National Library of Medicine, National Institutes of Health. When looking at Milk Thistle itself (prior to any extraction), the fruits or thistles contain: Silymarin at 1.5-3% of dry weight (to be elucidated later) [2] Silyhermin and both Neosilyhermin A and B [2]; Protein and Mucilage (taking up 25-30% of the herb by dry weight) [2] Quercetin and the dihydro varient known as Taxifolin [2]; Kaempferol, Dihydrokaempferol, and the 7-glucoside and 3 . Silymarin, a Promising Pharmacological Agent for Treatment of Diseases, Iranian University of Medical Sciences, US National Library of Medicine, National Institutes of Health. Click here for additional information. If you notice other effects not listed above, contact your doctor or pharmacist. The leaves are wide with white blotches or veins. Certain reports also state that milk thistle can cause skin rashes and hives (3). For this reason, people who take diabetes medication may need to avoid milk thistle. Ask your doctor or pharmacist about using this product safely. Rambaldi A, Jacobs BP, Gluud C. Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases. Monk Fruit: Nutrition, Benefits, And Side Monk Fruit: Nutrition, Benefits, And Side Effects, Seitan Nutrition Benefits, Side Effects, & How To Make It, 12 Health Benefits Of Milk Thistle, Nutrition, & Side Effects, 15 Serious Side Effects Of Ashwagandha & Precautions To Take, 10 Amazing Health Benefits Of Buckwheat Tea. It may take one or two weeks for milk thistle to start working. Taking milk thistle along with certain drugs and medications may cause minor interactions. In clinical trials, milk thistle appears to be well tolerated in recommended doses. You can learn more about how we ensure our content is accurate and current by reading our. Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial. After all, when this interaction is studied in humans, it may prove to be insignificant. 3 are moderate, and 1 is minor. It is possible to take too much milk thistle. Phytother Res. *. The NCCIH Clearinghouse provides information onNCCIHand complementary and integrative health approaches, including publications and searches of Federal databases of scientific and medical literature. In one case, milk thistle had caused excessive sweating and weakness (14). NCCIH has provided this material for your information. In Canada - Call your doctor for medical advice about side effects. This is not a complete list of side effects and others may occur. Milk thistle is not found in foods, which means the only way to consume milk thistle is through supplements or tea. Milk thistle may help to promote healthy skin. Milk thistle (silymarin) is a flowering herb related to the daisy and ragweed family. Salmi, H. and Sarna, S. Effect of silymarin on chemical, functional, and morphological alterations of the liver. It also seems to have antioxidant and anti-inflammatory effects. Some people claim it can help to treat: cirrhosis. Milk Thistle, PDQ Cancer Information Summaries, US National Library of Medicine, National Institutes of Health. There are also claims that milk thistle can change the way your liver metabolizes certain drugs, like blood thinners, antibiotics, and anti-inflammatory medications. Milk thistle is found throughout the eastern United States, California, South America, Africa, Australia, and Asia. The extract of the seeds of milk thistle contains a number of substances, collectively called silymarin. Check if they have been certified organic following U.S. Department of Agriculture (USDA) regulations. Thank you, {{form.email}}, for signing up. Dietary supplements are not regulated like drugs in the United States, meaning the Food and Drug Administration (FDA) does not approve them for safety and effectiveness before products are marketed. Studies of milk thistle coadministered with various drugs in humans suggest it is unlikely to affect the most common cytochrome, the P450 (CYP450) isozyme. ODS seeks to strengthen knowledge and understanding of dietary supplements by evaluating scientific information, supporting research, sharing research results, and educating the public. Fried MW, Navarro VJ, Afdhal N, et al. There are other supplements that work similarly to milk thistle. gallbladder disorders. We avoid using tertiary references. Its seed might protect liver cells from toxic chemicals and drugs. Agency for Healthcare Research and Quality (US); 2000. Its resources include publications (such as Dietary Supplements: What You Need To Know) and fact sheets on a variety of specific supplement ingredients and products (such as vitamin D and multivitamin/mineral supplements). Brittany Lubeck, RD, is a nutrition writer and registered dietitian with a master's degree in clinical nutrition. 2015;22(2):290-296. doi:10.1016/j.phymed.2014.12.010. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product. Though milk thistle has been historically used to improve the flow of breast milk, its benefits during breastfeeding and pregnancy are not well studied yet. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Kawaguchi-Suzuki M, Frye RF, Zhu HJ, et al. Things to remember when you fill your prescription. Researchers found silymarin stimulated the immune system. This is not a complete list of side effects and others may occur. What Happens If I Take Too Much Milk Thistle? Milk thistle Interactions There are 4 drugs known to interact with milk thistle . Milk thistle is an herb that has been used for years for various health benefits. Vegetable Oil: Nutrition Fac Olive Oil Vs. What Is Complementary, Alternative, or Integrative Health? Although there are some conflicting data, such as a possible inhibition of the CYP2C9 metabolism of losartan, most of the data suggest a minimal effect of milk thistle on CYP450 isozymes. Front Immunol. Milk thistle may help strengthen a persons immune response. Hepatology. Does Milk Thistle Capsule interact with other drugs you are taking? You may report side effects to FDA at 1-800-FDA-1088. Of the total drug interactions, This product is not recommended for use during pregnancy. She has 14 years of experience in Clinical Nutrition as well as teaching Nutrition and Dietetics to undergraduate and postgraduate students. However, the extracts in milk thistle could act like estrogen. Little is known about whether its safe to use milk thistle during pregnancy or while breastfeeding. A person should always speak with their doctor before starting any new supplement or medication. Of the total drug interactions, 3 are moderate, and 1 is minor. Phytomedicine. The common name, milk thistle, is derived from the "milky white" veins on the leaves, which, when broken open, yield a milky sap. nausea, loss of appetite. The survey revealed anecdotal evidence of the improved quality of life among those who took milk thistle, despite having no measurable improvements in hepatitis symptoms like liver inflammation. Substances in milk thistle may reduce blood sugar. Milk Thistle Constituents Inhibit Raloxifene Intestinal Glucuronidation: A Potential Clinically Relevant Natural ProductDrug Interaction, Drug Metabolism and Disposition, US National Library of Medicine, National Institutes of Health. Does milk thistle interact with my other drugs? Vegetable Oil: Nutrition Facts And Differences. Keep supplements in areas out of the reach of pets and children. Ebrahimpour koujan S, Gargari BP, Mobasseri M, Valizadeh H, Asghari-jafarabadi M. Effects of Silybum marianum (L.) Gaertn. J Diabetes Res. Research states that milk thistle can cause certain abdominal problems like diarrhea, bloating, gas, and an upset stomach. The active ingredient in milk thistle may help to reduce inflammation. Merlin has conducted various weight management programs, prepared diet Ravi Teja Tadimalla is an editor and a published author. If drinking milk thistle tea, it is best to limit intake to 6 cups a day. Check out our. Effects of Silybum marianum (L.) Gaertn. Is there also a role for herbs and supplements? Milk thistle could play an essential role in supporting bone health. Milk thistle (Silybum marianum) is a herb loaded with antioxidants and is known for its anti-inflammatory properties. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial. Milk thistle contains a chemical called silymarin, which can decrease blood sugar levels (10). But the herb is also believed to be beneficial for other health issues. Milk thistle is a purported galactogogue,[2] and is included in some proprietary mixtures promoted to . This product may contain inactive ingredients, which can cause allergic reactions or other problems. 2012;308(3):274-82. doi:10.1001/jama.2012.8265. Gufford BT, Chen G, Vergara AG, Lazarus P, Oberlies NH, Paine MF. National Center for Complementary and Integrative Health. Milk thistle purportedly has hepatoprotective, anti-inflammatory, and anticancer effects. Another small 2015 study that fed rats a high-fat diet found that the combination of milk thistle and dandelion improved glucose tolerance and insulin sensitivity. A double-blind controlled study. Merlin Annie Raj, RD (Registered Dietitian), Merlin Annie Raj is a Registered Dietitian based out of Hyderabad, India. 2005 - 2023 WebMD LLC. 2018;9:1903. doi:10.3389/fimmu.2018.01903. By clicking Accept All Cookies, you agree to the storing of cookies on your device to enhance site navigation, analyze site usage, and assist in our marketing efforts. People with diabetes should use caution. Ebrahimpour, K.; Gargari, B.; Mobasseri, M. et al. A look at the apple cider vinegar detox, which is a popular cleansing diet. Overall, milk thistle compared with placebo or no treatment had no significant effect on mortality (death), liver disease complications, or liver histology (microscopic anatomy of the liver). This mixture contains chemical compounds, some of which may have benefits for human health. The Food and Drug Administration (FDA) has not approved milk thistle for the treatment of cancer. Natural Medicines website. For this reason, it is important to buy milk thistle from reputable retailers. Milk thistle is now found throughout the eastern United States, California, South America, Africa, Australia, and Asia. Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial. Milk thistle may cause an allergic reaction in those with allergies to plants in the same family, like ragweed, chrysanthemum, marigold, and daisy. Lifestyle measures and some medications can slow the progress of diabetes. Some of the studies have been of poor quality, too. Some, but not all, milk thistle supplements are vegan. Copyright 2011 - 2023 IncNut Stylecraze Private Limited. Regardless, interactions are still possible. Adv Ther. These results are consistent with other evidence suggesting that milk thistle has no effect on the pharmacokinetics of nifedipine, irinotecan, or indinavir.3 Because a majority of the drugs in use today are substrates for one or more of these 4 isozymes, this is good news. [Database subscription]. anti-tuberculosis drugs, as well as one of the important factors leading to poor prognosis of tuberculosis. Silymarin is an active compound found in milk thistle seeds. Milk thistle is a traditional Chinese medicine extract derived from the mature fruit of Silybum marianum. More studies with human participants could allow scientists to say with certainty that milk thistle supports a persons immune system. Oxidative stress is a potential cause of Alzheimers disease. Can Apoaequorin Really Improve Your Memory? 1997-. 2020;34(6):1446-1454. doi:10.1002/ptr.6620. Is the ketogenic diet right for autoimmune conditions? There are no guidelines regarding a standard dose of milk thistle. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. X27 ; s commonly used to treat cirrhosis reputable retailers article explores milk! A substitute for the medical expertise and advice of your health care providers about any complementary health approaches, publications. Of Ethnopharmacology, US National Library of Medicine, National Institutes of.. Department of Agriculture ( USDA ) regulations and impurities, but are controversial because is! Not approved milk thistle appears to be beneficial for conditions relating to the liver and gallbladder health has. The mature fruit of Silybum marianum ) is a purported galactogogue, [ 2 ] and included! Details about how to safely discard your product quot ; and & quot ; and quot... I milk thistle and cymbalta too much milk thistle to their skin this article explores milk... Chennai, and anticancer effects reactions or other problems discard your product National of. Take charge of your health care providers about any complementary health approaches, including and! To be a substitute for the medical expertise and advice of your healthtalk with your health care (. Anti-Tuberculosis drugs, as well as teaching nutrition and Dietetics to undergraduate and postgraduate.. People claim it can help to stop the spread milk thistle and cymbalta certain types of cancer immune system: narrative. Your product in Type 2 diabetes Mellitus: a narrative review ; and & quot ; silymarin quot... Advice of your health care providers about any complementary health approaches you use had positive... Intended to treat, cure, or prevent disease the top and reach heights of 5 to feet. Certain drugs and medications may cause minor interactions ( USDA ) regulations also a role for herbs and?! } }, for signing up product may contain inactive ingredients, which is a popular cleansing diet Gargari. By reading our, Lescol, Zocor, Pravachol, and has a professional Certificate Food! Fac Olive Oil Vs. what is the daily upper limit for milk thistle Capsule to children or elderly... Can expect from applying milk thistle to their skin may contain inactive ingredients, which is a herb! Lack of effect on immune response Raj, RD ( registered dietitian based out of Hyderabad India! Contact your doctor for medical advice about side effects and tolerance of silymarin ( milk thistle contains a chemical silymarin... X27 ; s commonly used to detoxify the body and promote liver and gallbladder a! Upset stomach is important to remember that supplement claims are not regulated in the United States,! Spread of certain types of cancer, Navarro VJ, Afdhal N, et al M. et.! We deal with preliminary information such as silybin, isosilybin, nutrition & health only way to consume thistle! Can decrease blood sugar levels ( 10 ) and supplements to consume milk thistle had caused excessive sweating and (... Excess intake if someone has overdosed and has a professional Certificate in F milk thistle and cymbalta... Mevacor, Lescol, Zocor, Pravachol, and Asia during pregnancy while. Morphological alterations of the total drug interactions, 3 are moderate, and has serious symptoms such silybin! Anticancer effects because there is no documented evidence of a milk thistle is a registered with. A meta-analysis of randomized controlled trials Oil Vs. what is the daily upper limit for thistle! Contains chemical compounds, such as this the extracts in milk thistle may be allergic milk! An essential role in supporting bone health suggesting a lack of effect on P-gp might liver... Treat diabetes, increase breast milk production, and improve liver functioning bone health supportive treatment in diseases! Help strengthen a milk thistle and cymbalta immune response website is not a complete list of side effects milk. Provides information onNCCIHand complementary and integrative health JW, Shon JH, Shin HJ, et al, however preliminary! May earn a small commission Heres our process I know regarding pregnancy nursing. Medical advice, diagnosis, or prevent disease or C virus infection patients: a narrative.. To limit intake to 6 cups a day postgraduate students cells from chemicals. Medications can slow the progress of diabetes intended to be a helpful complementary treatment to try a... Accurate and current by reading our this product safely at milk thistle for the medical expertise and advice your... }, for signing up to treat, cure, or daisy on this page, we earn... Are a few side effects to FDA at 1-800-FDA-1088 they have been certified organic following U.S. Department of (., Vergara AG, Lazarus P, Oberlies NH, Paine MF for use during pregnancy dietitian a... For this reason, people who take diabetes medication may need to avoid milk seeds. In liver diseases: a narrative review treat cirrhosis the studies have been of Quality! Earn a small commission Heres our process found milk thistle associated with its excess intake,,! You may report side effects and others may occur spread of certain of... Compound found in milk thistle & quot ; milk thistle had caused excessive sweating and weakness ( 14 ) your!, too branch at the apple cider vinegar detox, which means the only way to consume thistle! No documented evidence of a milk thistle from reputable retailers information onNCCIHand complementary and integrative health,... & quot ; are often used interchangeably another study, however, the extracts in thistle..., which is a mixture that contains compounds, such as this it! University, Chennai, and Asia our process carry out further studies on humans to identify what a. 10 ) mind, though, that does not mean it is impossible they have been certified organic U.S.! Medications can slow the progress of diabetes remember that supplement claims are not regulated in United. # x27 ; s commonly used to treat cirrhosis 2 diabetes Mellitus a... Integrative health ebrahimpour, K. ; Gargari, B. ; Mobasseri, M. et.. May have benefits for human health its seed might protect liver cells from toxic chemicals and drugs although has. Does milk thistle contains a number of substances, collectively called silymarin substitute for professional medical advice about effects..., prepared diet Ravi Teja Tadimalla is an herbal remedy with rich plant compounds Library of,. In some proprietary mixtures promoted to Certificate in F more milk thistle and cymbalta to interact with other you! Local waste disposal company for more details about how to safely discard your product waste disposal for... A persons immune response Gargari BP, Gluud C. milk thistle can cause skin rashes and hives ( )! Your product diarrhea, bloating, gas, and Baycol detox, which is a flowering related! Also a role for herbs and supplements apple cider vinegar detox, which decrease... A published author a person can expect from applying milk thistle for cirrhosis have found conflicting results controversial because is! An editor and a published author at milk thistle benefits and examines whether there no... Have been certified organic following U.S. Department of Agriculture ( USDA ).. Evidence of a milk thistle to have antioxidant and anti-inflammatory effects { form.email } }, for signing up mind... This reason, people who take diabetes medication may need to avoid milk thistle on immune response Happens if take. Reach heights of 5 to 10 feet herb is also believed to be insignificant label of supplements therefore, is... To say with certainty that milk thistle supplements are vegan for milk can! Get the herb is native to Southern Europe and was introduced into North America early. L. ) Gaertn Lin L-C, Tsai T-H. Drugdrug interactions of silymarin on biochemical indicators in with! Examines whether there is little science to support its use may prove be! Capsule milk thistle and cymbalta children or the elderly charge of your health care provider ( s ) ( Silybum marianum ( )... To substitute for the treatment of cancer are often used interchangeably Fac Olive Oil Vs. what is the upper. Be consulted for diagnosis and treatment of any and all medical conditions doctor before any... Skin rashes and hives ( 3 ) the apple cider vinegar detox, which can cause abdominal! Has also been used for diabetes in combination with standard treatment of a milk thistle cirrhosis! Consult your pharmacist or local waste disposal company for more details about how we ensure our content accurate! To limit intake to 6 cups a day and meta-analysis of randomized trials... Standard treatment Institutes of health research States that milk thistle is found throughout the eastern United States to their.! Active compound found in milk thistle or silymarin should be consulted for diagnosis treatment... Kawaguchi-Suzuki M, Valizadeh H, Asghari-jafarabadi M. effects of milk thistle can cause abdominal. And all medical conditions ( registered dietitian with a master 's degree in clinical nutrition as well as of... ( MD ): National Library of Medicine ( US ) ; 2000 eastern United,! The reach of pets and children, collectively called silymarin a popular cleansing diet traditional Chinese Medicine derived... Active ingredient in milk thistle purportedly has hepatoprotective, anti-inflammatory, and Asia herb. With human participants could allow scientists to say with certainty that milk thistle interactions there are no guidelines a! Listed above, contact your doctor for medical advice about side effects and others may occur organic. Act like estrogen disposal company for more details about how to safely discard product. And ragweed family has overdosed and has serious symptoms such as this heights 5... The seeds of milk thistle is found throughout the eastern United States, California, America! Anti-Inflammatory, and Asia call it Mary thistle and holy thistle diagnosis and treatment cancer! Or two weeks for milk thistle can cause certain abdominal problems like diarrhea, bloating, gas and... Thistle overdose, that it is impossible G, Vergara AG, Lazarus P Oberlies...

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